Pathogenesis of hepatic sinusoidal capillarization in hepatic cirrhosis

The Pathogenesis of Hepatic Cirrhosis

. evoked the interest of doctors in this hospital. Dr. K. T. Kurian, my co-worker in the medical wards, has had occasion to note the diet of the people in three or four centres, and he has intimate knowledge of the habits and natural conditions of this northern part of Travancore. In the assessment and evaluation of the setiological factors, therefore, his information and help have been found v...

Human recombinant endostatin Endostar attenuates hepatic sinusoidal endothelial cell capillarization in CCl4‑induced fibrosis in mice.

The aim of the present study was to detect the effect of the recombinant human endostatin Endostar on hepatic sinusoidal capillarization in CCl4‑induced murine models of liver fibrosis. The liver fibrosis model was induced in BALB/c mice using intraperitoneal injection of CCl4 for 6 weeks. Animals were divided into the following six treatment groups: Group 1, normal animals; group 2, CCl4‑induc...

Vatalanib, a tyrosine kinase inhibitor, decreases hepatic fibrosis and sinusoidal capillarization in CCl4-induced fibrotic mice

Among the various consequence arising from lung injury, hepatic fibrosis is the most severe. Decreasing the effects of hepatic fibrosis remains one of the primary therapeutic challenges in hepatology. Dysfunction of hepatic sinusoidal endothelial cells is considered to be one of the initial events that occur in liver injury. Vascular endothelial growth factor signaling is involved in the progre...

Hepatic Cirrhosis

TIhC 0CCLPTen1CC inI h1o0Spitall Within a conmparatively shiort space of time of touIr unuISula.l examllples of cirrhosis of tihe li\-er in-younil-chil(lren has le(d us to Iake this comlnlLI1liunictionl. Disorders of tihe liver in chil(lhoo(l ha\ve iii recent N'ears not attracted imiuchi attentioni in tihis country, and we feel that tlhe mere ventilation of the suLb)ject, thIough,0LI we mXVn ha...

[Hepatic cirrhosis].